Sentence examples for components or pathways from inspiring English sources

However, some diseases are the consequence of multiple components or pathways and not the result of a single mediator; thus, blocking at a single point may not optimally control disease.

In contrast to master regulators the so called mid-level regulators can not only be mediators of different incoming regulatory signals but also influence multiple downstream components or pathways.

This may be due to more efficient intracellular trafficking and clear-up of Aβ, or the components or pathways that induce Aβ build-up or production [ 24- 27].

Although it is difficult to integrate all epidemiologic data into a single biologic model, it is clear that several important components or pathways exist.

Genetic suppressor and enhancer screens are a powerful way to explore how complex biochemical processes work in vivo and in particular how processes are controlled and interact with other cellular components or pathways.

In designing ABMs, hypotheses can be developed as to how individual components or pathways contribute to tissue‐ or organism‐level effects: hypotheses that may be examined further with experimental or clinical studies.

TF TF binding site interactions were used to list transcriptional connections between TFs and genes encoding signaling components or pathway interactors.

They also introduced an "ethanol producing component," or pathway.

Collectively these Ir complexes show potential polypharmacology, the targeting of more than one biological component or pathway.

This finding emphasizes that signal-to-response relationships will in general require multiple signaling pathways to be included in the model and that attempts to predict how cells will behave on the basis of alterations (whether genetic or therapeutic) to a single component or pathway will most probably be in vain.

The analysis was performed on 459 a priori defined gene sets (a gene set is defines by genes involved in the same biological process, molecular function, cellular component, or pathway) that were downloaded at the Molecular Signatures Database site http://www.broad.mit.edu/gsea/msigdb/index.jsp.jsp