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Furthermore, it identified the ranked immunological components of the expression profile of a tumor with its associated networks of interactions.
The estimated factors in the model capture components of the expression heterogeneity independent of the effects of the variable of interest.
Additionally, we calculated principal components of the expression data residualized for its first five principal components to account for unmeasured batch effects as outlined elsewhere (12).
To try to distinguish the genetic from the environmental components of the expression patterns of HERV-W gag elements, we employed cultures of human primary fibroblasts from healthy individuals and subjected them to serum deprivation.
Relationship between genes and treatments as well as the magnitude of their association can be clearly visualized in the bi-plot generated by the first two principal components of the expression matrix, with rows and columns representing genes and treatments (control, cold and salinity) replicates, respectively.
Even though a subset of female-enhanced transcription during diapause will concern the early stages of egg development, other components of the expression profile will also be linked to maintaining a diapausing state and developmental arrest, which is discussed below in more detail.
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Association between each module's first principal component of the expression data and clinical improvement was tested in the three cohorts.
Tomfohr et al. [28] and Bild et al. [23] used the first principal component of the expression profile of the member genes to estimate the activity of a given pathway.
Rather, it identifies and grades the magnitude of the immune component of the expression profiles.
The module eigengene is defined as the first principal component of the expression matrix of the probes within the module.
The third component of the expression data was dominated by the melanoma and leukemia lines' expression, explaining 5.2% of the variance.
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elements of the expression
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factors of the expression
components of the declaration
segment of the expression
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components of the voices
components of the mixture
components of the craft
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