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The goal of this study is to propose a new method of static analysis in order to determine the arrangement of the various components of planar mechanisms subjected to mechanical loadings.
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The core components of the planar cell polarity (PCP) signaling system, including both transmembrane and peripheral membrane associated proteins, form asymmetric complexes that bridge apical intercellular junctions.
In ciona notochord cells, components of the planar cell polarity pathway show asymmetric localization along the mediolateral axis during cell intercalation and anteroposterior axis after cell intercalation [27].
This approach has met some success recently when Sasselli et al. [[ 7]] demonstrated that core components of the planar cell polarity (PCP) pathway are necessary for aligning neurites along the rostrocaudal axis of the gut.
Components of the planar cell polarity (PCP) pathway are required for the caudal tangential migration of facial branchiomotor (FBM) neurons, but how PCP signaling regulates this migration is not understood.
Prickle1 (Pk1), a core component of the planar cell polarity (PCP) pathway, is essential for epiblast polarization before gastrulation, yet the roles of Pk family members in early mouse embryogenesis are obscure.
A third component of the planar cell polarity pathway, grainy head (grh), was identified from the P-element screen.
PK1 is a core component of the planar cell polarity network that regulates tissue polarity.
PK is a core component of the planar cell polarity (PCP) pathway that regulates cell movement and tissue polarity.
The latter authors demonstrated specific dependence of VANGL2, a key component of the planar cell polarity signaling pathway, on the SEC24B paralog for ER exiting (Merte et al., 2010).
The large colored spot diagrams on the left illustrate how the large astigmatism component of the planar configuration not only enlarges the actual spots, but also displaces them (beam wandering).
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