Sentence examples for components of macromolecular from inspiring English sources
It is becoming clear that the functions of many proteins occur as components of macromolecular complexes.
Components of macromolecular complexes, such as the ribosome and proteasome are among the most highly enriched terms, which is expected since these proteins need to be produced in stoichiometric amounts and are therefore likely to be coregulated.
It simply brings up a possibility of buffering that can explain why heterozygous deletions of genes encoding components of macromolecular complexes do not always lead to an abnormal phenotype (i.e. the wild-type allele is dominant).
Gene ontology analysis revealed that components of macromolecular complexes were significantly enriched (369 of 550, p value = 5.1 E−32), including all ribosomal subunits detected (113 of 550, p value = 6.2 E−43).
Vault ncRNAs were first described as components of macromolecular ribonucleoprotein complexes termed vaults, which are conserved organelles found in most species (Kedersha et al., 1990; Kedersha and Rome, 1986).
Cells that are not growing are expected to have a relatively low requirement for components of macromolecular synthesis; on the other hand, protein synthesis is required during differentiation, since new proteins are needed.
The individual components of these macromolecular complexes appear to influence the stability, the trafficking, the localization and/or the biophysical properties of the channels.
Other things that may contribute include: the presence of the F plasmid; differences in the organization of the genome due to large insertions and deletions (Table S1); small differences in components of the macromolecular synthesis machinery (e.g. RpoD, RpoS, RpsG, RF-2; Table S5).
They also interact with transcriptional co-regulators such as the nuclear hormone receptor co-repressor (N-CoR) and silencing mediator of retinoid and thyroid hormone receptors (SMRT), both components of a macromolecular repressor complex containing mSin3 and histone deacetylase (HDAC) [6], [7].
These enzymes are components of conserved macromolecular complexes that require the effector protein WDR5 (WD40 repeat protein 5) for assembly and activity [ 3].
The expression of NHERF1 is closely regulated in alveolar cells during pregnancy and rises in parallel to the PRLR expression but also to that of the other structural components of the macromolecular complex.
