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All of the other components of bone, organic and inorganic, are of course also essential for bone integrity, but the importance of availability of structural materials is most easily illustrated by consideration of calcium balance (dietary intake versus excretory output).
However, the major metabolic activity in bone is carried out by osteoblasts, which generate the protein matrix, and osteoclasts, which are large multinucleated cells that digest and dissolve the components of bone.
Basic components of bone fibrils are collagen, mineral and water.
Other organic components of bone may be bound to fibrils and exert additional effects.
The major components of bone tissue engineering are the scaffold, cells, and growth factors.
Direct measurement of these components of bone strength may result in improved fracture risk prediction or therapeutic monitoring.
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Chemically appetites are similar to components of bones and hard tissues of mammals classified as biomaterials [1, 2].
For example, nanoparticles of calcium hydroxyapatite, a natural component of bone, used in combination with collagen or collagen substitutes could be used in future tissue-repair therapies.
A successful graft requires stem cells--a component of bone marrow which has the ability to reproduce itself indefinitely--from a genetically compatible donor to be infused into a vein; once in the bloodstream, the cells will home in on the marrow space.
It is the main inorganic component of bone tissue [2 4].
Angiogenesis is a key component of bone formation.
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