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Alternatively, or in addition, the autophagic and proteosomal responses may be directed at clearing cellular components damaged by ROS and preventing toxicity arising from the accumulation of damaged organelles [ 75– 75].
Such a validation exercise allowed us to prove that the TCD is highly accurate also in estimating fatigue damage in notched components subjected to VA loading: this result is definitely encouraging, fully supporting the idea that the TCD can safely be used to design real notched components damaged by in-service VA load histories.
It is likely that stochastic factors will also play an important role since the actual components damaged will have a large effect on subsequent outcomes.
In addition, enrichment of chaperone proteins and proteases in the Reaeration Response suggests an effort by MTB to repair or replace proteins and cellular components damaged by either hypoxia and/or re-introduction of oxygen.
GPX breaks down hydrogen peroxide [ 27] and GST conjugates reduced glutathione to xenobiotics or cellular components damaged by ROS [ 28].
The data agreed with our general assumptions that oocysts need to activate pathways to repair DNA, other macromolecules, and cellular components damaged by UV-irradiation.
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Radicals are unstable and readily react with cellular components, damaging them.
Otherwise, static buildup from even just walking around might jump from your fingers to electronic components, damaging them in the process.
A genetic algorithm is adopted to optimize the rule weights associated to the components' damage levels.
The paper investigates the effect of the number and weights of fuzzy rules to relate each components' damage level to the global damage level using a single-antecedent weighted fuzzy rule.
However, it is unclear if NPC components are damaged directly by free radicals or whether loss of NPC components is caused by other mechanisms.
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