Sentence examples for component trial from inspiring English sources
A notable component trial of the meta analysis was the Perindopril pROtection aGainst REcurrent Stroke Study (PROGRESS) (PROGRESS 2001).
The number of events and total number of patients in each arm were extracted for each component trial.
During each simulation, we randomly sampled one SMD and the corresponding standard error for each component trial in a specific meta-analysis.
Phase 4 added further compound and component trial types to Phase 3, but no further complete patterning problems (see Table 3).
For each component trial, we extracted the following data: sequence generating, allocation concealment, blinding, incomplete follow-up data, intention-to-treat analysis, sample size calculation, and year of publication.
Inclusion criteria were as follows: critical care meta-analyses involving randomized controlled trial; the end points should include mortality; at least one component trial had more than 100 subjects per arm on average.
The prognostic value of eGFR was not significantly different among the three component trials.
METHODS AND RESULTS: The Candesartan in Heart Failure:Assessment of Reduction in Mortality and Morbidity (CHARM) program consisted of three component trials that enrolled patients with symptomatic CHF, based on use of ACE inhibitors and reduced (< or =40%) or preserved LVEF (>40%).
There was no heterogeneity of the effects of candesartan in preventing AF between the 3 component trials (P =.57).Treatment with the angiotensin receptor blocker candesartan reduced the incidence of AF in a large, broadly-based, population of patients with symptomatic CHF.
CHARM provided the opportunity to prospectively determine the effect of candesartan on the incidence of new AF in this CHF population.7601 patients with symptomatic CHF and reduced or preserved left ventricular systolic function were randomized to candesartan (target dose 32 mg once daily, mean dose 24 mg) or placebo in the 3 component trials of CHARM.
The inner surface of the empty acetabulum was sized with acetabular component trials.
