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Second, efficacy, or a component of efficacy (response efficacy or self-efficacy) had to be manipulated.
Since Spencer et al [ 11] administered MPH three times daily and the long acting formulation of OROS-MPH was designed to provide day-long coverage, these results suggest that a key component of efficacy observed in these studies may also be day long pharmacological coverage.
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For example, when considering the intrinsic value component "improvement of efficacy", it is generally agreed that, all else being equal, an intervention that brings major efficacy improvement has a higher value than one with minor improvement.
In this paper, we categorize community-based vaccine efficacy studies based on the specific component of vaccine efficacy that was reported: VE S, VE P, VE SP, VE I.
While the mode of action of a disease modifying therapy is a key component of its efficacy, local retention of the factor is also thought to be critical.
In the direction of multipurpose technologies (MPTs), attempts are also being made to develop microbicides with an added component of contraceptive efficacy.
92, 96, 97 These data suggest the prostate-specific component of taxane efficacy may be lost in tumors that have developed resistance to AR pathway inhibition.
These data indicate that overall product formulation is a critical component of product efficacy, and it is inappropriate to assume product performance based solely on the identity and concentration of active ingredients.
Moreover, this model predicts that at least a component of the efficacy of BCDT is derived from its ability to clear B-in from lymphatic endothelium and thus "unclog" the sinuses and restore lymphatic flow.
The Fear for partner rejection factor is suggestive of Bandura's physiological feedback component of self-efficacy, as was implied in the studies of Barkley and Burns [ 8].
Own capacity also has a component of self-efficacy (I felt capable) and coping (I felt that I handled the situation well) and thus likens the domain-specific Childbirth Self-efficacy Inventory scale [ 18].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com