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By simulating a component of diabetes, and looking at the global response on mice resistant to the disease, by virtue of a small genetic difference, we were able to identify key factors in disease progression.
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However, although RAGE has been implicated in atherosclerosis, and the vascular component of diabetes mellitus and renal disease, RAGE Gly82→Ser polymorphism showed no association with CV disease in the general population [ 21].
Future research is needed to examine whether taking action on the basis of these results is effective in improving weight loss outcomes, a key component of diabetes prevention and treatment.
Reduced insulin sensitivity is a key component in the pathogenesis of diabetes, and diabetic nephropathy is a leading cause of end-stage renal disease (ESRD) (1).
(E) MNT is an integral component of diabetes prevention, management, and self-management education.
7 8 Nutrition therapy is an integral component of diabetes prevention, management and self-management education.
Physical activity is a key component of diabetes mellitus (DM) and arthritis management (1– 3).
Clinical practice guidelines recommend physical activity as an important component of diabetes management (2) and for prevention of cardiovascular complications (3), but only 16% of individuals aged 65 74 years engage in at least 30 min of moderate activity ≥5 days/week (4).
Compelling evidence from past research and from this study indicates that regular physical activity is a key strategy in the prevention of diabetes and is an essential component of diabetes care.
There is more to the environmental component of obesity, diabetes and metabolic syndrome than overeating and poor nutrition, lack of exercise and changes in lifestyle.
Self monitoring of blood glucose is well-established as an important component of diabetes management for insulin-treated patients [ 4] and has also been found to be important in some studies of non-insulin dependent patients [ 5, 6].
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