Sentence examples for component of cigarettes from inspiring English sources
Our laboratory has previously demonstrated in a rat model that maternal exposure to nicotine, the major addictive component of cigarettes, during pregnancy and lactation results in postnatal obesity and impaired glucose homeostasis in adult offspring [14], [15].
In animal and human studies, exposure to nicotine, the major active component of cigarettes, can exert immunosuppressive (3, 27) as well as anti-inflammatory effects (1, 2, 28).
Nicotine, which is the primary psychoactive component of cigarettes, can enhance the surface expression of some endothelial cell inflammatory mediators[ 7] and can accelerate some cardiovascular disease formation[ 8].
The aim of this study is to evaluate the effect of nicotine, a major component of cigarette smoke, on interleukin-8 (IL-8) production and cellular signalling via nicotinic acetylcholine receptors (nAChRs) in human gingival epithelial cells (HGECs).
We tested the effect of nicotine (a key component of cigarette smoking) on the therapeutic effects of human embryonic stem cell-derived endothelial cells (hESC-ECs).
Both AKR1C isoforms and AKR1B10 catalyze oxidative activation of xenobiotic proximate carcinogen PAH trans-dihydrodiols (such as B[a]P, a component of cigarette smoke), to generate reactive ortho-quinones, and mediate redox cycling with ROS amplification [98].
In addition, the effect on female current smokers, though significant, was not complete, and suggests only a subset with a particular genetic background or who are within a dose-response window, are responding to a component of cigarette smoke, and this fraction will vary among patient cohorts.
Nicotine is the major toxic component of cigarette smoke and may interact with the nicotine acetylcholine receptor in many cells.
