Sentence examples for component endpoint from inspiring English sources

HRQoL is recognized as a component endpoint for cancer therapy approvals by the American Society of Clinical Oncology and the FDA.

Further analyses of the component endpoint of MI [ 7, 8] demonstrated that prasugrel, both LD and MD, significantly reduced the ischemic event of MI compared with the clopidogrel LD and MD during the very early phase (days 0 3), the early phase (days 0 30), and the later MD phase (days 30 450) of the study.

The event rates of study patients according to country-level HDI groupings are presented in table 3. Rates of occurrence of the composite endpoint and the individual component endpoint of MI differed significantly among groups, with the high-HDI country group having the lowest event rate for the composite endpoint and the medium-HDI country group having the lowest rate of MI.

A similar trend was observed for both component endpoints.

The efficacy outcomes evaluated for this study were (1) the primary efficacy composite endpoint of cardiovascular death, MI, or stroke, and (2) individual component endpoints of cardiovascular death, all MI events, all stroke events and all-cause death.

However, such measures may prove challenging for the interpretation of results, particularly if the component endpoints are of widely differing importance to patients and the magnitude of effect differs markedly across components [ 21- 23].

Of note, the component endpoints of urgent target vessel revascularization (uTVR) and stent thrombosis (discussed later) were also significantly reduced both during the very early period and the maintenance phase with prasugrel treatment [ 7].

In general, if analysis of scores for the individual component endpoints of a composite shows the improvement is driven primarily by a single domain (e.g., performance of a specific activity), the findings for the composite score would not support a general claim (e.g., psychological or emotional benefit, or even general physical state if all that is shown is symptom improvement).

Because this study was concerned with postural control, we chose to focus on the static component of endpoint impedance, endpoint elasticity or stiffness.

The purpose of this study was to determine if posture selection is a critical component of endpoint stiffness regulation during unconstrained tasks.

Because most studies examining the control of limb stiffness have constrained limb posture, it is unclear if posture selection is a critical component of endpoint stiffness regulation during more natural tasks in which the kinematic redundancies of the arm can be exploited to change posture without altering endpoint location.