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As for C/EBP isoforms, it is not possible to identify any specific ATF component candidate based on binding site information alone, since all members of the ATF family bind to the same consensus DNA sequence (TGACGTCA).
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They are particularly useful in situations where the pool of component candidates is limited, for example in the case of a urine sample.
Beyond in-silico preliminary analyses to avoid introducing potentially harmful peptide-vaccine sequences (e.g., those similar to epitopes of self, food or common environmental components), candidate vaccine peptides could be incorporated into immunogens for producing antipeptide monoclonal antibodies as candidate therapeutic or prophylactic agents.
The output of the "Scene analysis" component contains candidate blocks.
They are less certain about the political gains of really fighting for this component of candidate Obama's health plan.
Components which do not have an incoming edge from any other component are candidate starting points.
In addition to gene related information, we included gene ontology based information such as biological function, process and molecular component of candidate genes from Gene Ontology database, Amigo (Release 2008-04-10) [ 40].
To the cellular component ontology, candidate genes were enriched in membrane and vesicle related cellular component including the membrane-bounded organelle (GO: 0043227), intracellular membrane-bounded organelle (GO: 0043231), cytoplasmic part (GO: 0044444), vesicle (GO: 0031982), plastid (GO: 0009536) and membrane-bounded vesicle (GO: 0031988).
The multi-facet Rasch model allowed the data to be broken down into three separate components of candidate, examiner and station, along with separate measures for the several components of the four-point marking scheme.
Most of these antigens are strongly recognized with high IFN-γ production in TB patients or infected individuals [ 23- 28] and are key components of candidate TB vaccines [ 29- 39] or form part of antigen cocktails that are used in diagnostic tests.
Qualitative model learning focuses on the exploration of components in candidate biochemical models.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com