Ant samples used in this study comply to the regulations for export and exchange of research samples outlined in the Convention of Biology Diversity and the Convention on International Trade in Endangered Species of Wild Fauna and Flora.
This study complies to the RATS guidelines for reporting qualitative studies.
Patients may also be excluded if they are thought to be less likely to comply with the study requirements or more likely to have co-morbidities that could confuse research results [ 16].
Patients were required to be postmenopausal females (no spontaneous menses for ≥ 1 year; LH and FSH levels > 40 IU/L; or bilateral oophorectomy prior to breast cancer diagnosis) older than 55 years with primary invasive breast cancer, to give prior written informed consent and to be able to comply with the study protocol.
Returning for a clinical visit at least once within six months was perceived as having the willingness to comply with the study schedule; failure to attend subsequently may indicate loss of motivation due to constraints associated with the health system.
They also had to be willing to comply with the study procedures.
The main bias is that some teachers failed to comply with the study protocol, leading to incomplete data collection for certain aspects of the study, highlighting the difficulties of working with teachers who are sometimes unwilling to comply with study protocols.
None of these conditions or features considered to potentially compromise the ability to comply with the study were exhibited by any of the IBS patients.
The per protocol (PP) population excluded major protocol violators (failure to meet the inclusion/exclusion criteria, to comply with the study medication or use of other vaccinations or antibiotics two weeks before until 2 weeks after vaccination, or use of antacids or proton-pump inhibitors prior to vaccination and/or did not provide samples for the ELISAs).
To participate in this study, subjects had to be 18 years and older, be able to comply with the study protocol, and be weight stable over the preceding three months.
To date 13% have dropped out, on average within the first 6 weeks (5.9±4.0, weeks, mean±SD, min 0.4-max 15.4 weeks) after recruitment (main reasons include: difficult to give daily drops, too busy to comply with the study procedures).
