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Genetic studies are less susceptible to confounding than observational epidemiology [21] and may offer a complimentary study design [22].
The complimentary study examined the function of stromal PHD2 in regulating tumour metastasis.
CEUS was never performed as a sole imaging study but rather as a complimentary study to MDCT or MRI.
A complimentary study of the ecological niche differentiation in these populations shows that the demes of chimpanzees found in this study also occupy significantly different niches [ 53], suggesting that environmental variation contributes to driving the differentiation of these populations.
Furthermore, in another complimentary study we found significant associations between genetic differentiation in these three demes and environmental variation across the study area [ 56], which led us to conclude that these populations likely follow a pattern of isolation-by-environment [ 57], a relationship between populations that arises as a result of local adaptation to different environments.
However, a complimentary study by Jeffrey et al in which transgenic mice expressing PrPC only in astrocytes did succumb to disease, albeit following an extended incubation period, suggests that the mechanisms of cell death are complicated, and not restricted to a neuronal response [ 50].
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For comparison, complimentary studies were conducted with water-soluble electron donors (acetate and dextrose).
Two complimentary studies in the Gulf Coastal Plain of the southeastern US were designed to test whether harvest intensity (level of biomass removal) could have a negative long-term impact on site productivity.
Complimentary studies using cancer-prone Trp53+/− mice demonstrate F-FDG injections of 0.75 MBq (10 mGy whole body dose) increased the latency of some types of cancers.
Importantly, complimentary studies with SK inhibitor SKI-II and the SK2-specific inhibitor ABC resulted in significant inhibition of virus infection, further confirming the siRNA experiments.
Data were obtained from two existing complimentary studies (the 2007-NSMHWB and the Australian Rural Mental Health Study, ARMHS) to undertake parallel cross-sectional analyses to explore the determinants of suicidal ideation and suicide attempts across geographical regions.
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