In this letter, we discuss the nature of the complications and the implications for patient selection.
Burden of care, treatment duration, long-term complications, and financial implications should be considered [ 65, 66, 72, 73].
5 Although complications are generally a reported parameter, the severity of the complications and the implications for the patients have often not been described sufficiently.
The second finding is also important because the association of macro-vascular co-morbidities with worsening eGFR relates to both the underlying pathophysiology of these complications and the implications for those with eGFRs <60 ml/min.
While the questionnaires provide some indication of overall parental understanding of the anatomy and the condition (ie, correct name of diagnosis or correct use of diagrams), a deeper appreciation of the complications and lifestyle implications does not emerge from this kind of assessment.
11 Chronic dependence on mechanical ventilation is not only a major medical problem, 2 but also produces extreme discomfort for patients, with important physiological complications and negative social implications and restrictions.
9– 13 With the growing population of elderly patients with cancer and other chronic diseases, modern medicine will need to address multiple medical problems at once, focusing on mortality, treatment complications, quality of life, and implications for screening.
Malaria remains an important problem in the world starting with the accuracy of clinical diagnosis, the necessity of laboratory confirmation, prevention and treatment of complications, social implications of morbidity and mortality.
The debate about screening examinations should consider not only SCD, but the possible cardiac structural changes caused by sport activities and implications for complications in long-term follow-up of athletes.
And as the government begins its abrupt retrenchment, the implications, complications and confusions in the process are beginning to emerge.
