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The major complication in identifying mutant genes using GINI is the fact that too many genes that do not contain nonsense mutations show mRNA accumulation following the blocking of NMD with emetine or small interfering RNA against hUpf1 and hUpf2 genes, the major regulators of NMD.
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As noted in the literature, there are many complications in identifying the impact of a specific study.
Further complications arise in identifying pregnancy-associated cancers from hospital data due to the inability to determine the duration of pregnancy in weeks of gestation, resulting in an imprecise pregnancy exposure period [ 8].
MRI may have a particular clinical role in identifying complications of gout.
Further studies are warranted to determine which methods of fetal movement counting prove most effective in identifying complications (sensitivity and specificity) early enough for interventions to prevent stillbirth, as well as acceptability to and feasibility for women.
In contrast to previous studies which did not find information on the character, timing and complications of cough useful in identifying the underlying cause, [ 30] we have shown that important diagnostic information is contained in the presenting complex of symptoms which are usually associated with the common causes of cough.
We theorized that identifying ACS-NSQIP preoperative data points predictive of patient outcomes would assist in identifying potential complications earlier.
However, the growing body of evidence suggests a minor role for CRP compared with serum PCT in identifying infectious complications in this setting.
CE-MRC imaging combined with T2w-MRC can be helpful in identifying biliary complications after liver transplantation.
In part, this is because cancer specialists have difficulty in identifying emotional complications and tend to have communication behaviours that systematically focus on physical rather than psychological concerns (Durkin et al, 2003).
More frequent screening may be beneficial in identifying such complications earlier, although patients with diabetes would continue to receive annual check-ups for their condition even with a reduction in retinopathy screening, and therefore such risk factors could be identified at these sessions.
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