Exact(4)
One day, I asked Kaptchuk how a man who practiced acupuncture and dispensed herbs, rather than earning a Ph.D. in biology or statistics, had learned to design complicated trials.
The trial was conducted in the glare of international attention and the focus of television cameras, which must have added to the inherently heavy rigours that are brought to bear upon trial courts in conducting lengthy and complicated trials.
"I don't ever recollect getting to this stage in any trial, even in far more complicated trials than this one, and, after two days of deliberations, a list of questions of this very basic kind illustrating that at least some jurors do not seem to have grasped it," he said.
Thus, a phase IV study basically aims to effectively and positively affect clinical decision-making by gathering real-life data as much as possible As a consequence of the therapeutic nature of phase IV whose goal is to gather (real-life) data that informs clinical decisions, the common setting for these usually large and less technically complicated trials is the physician's clinic.
Similar(56)
"It's a hugely complicated trial and the testimony is laden with military titles and acronyms," he said.
In dissent, Justice Breyer wrote that criminal fines have historically been treated differently from other punishments and that the majority decision needlessly complicates trials.
WASHINGTON -- A federal appeals court decision to overturn the conviction of Salim Hamdan, Osama bin Laden's driver, may vastly complicate trials for many of the remaining terrorist suspects at Guantanamo Bay, and make even more untenable any solution for dealing with those who can neither be tried nor released.
With this understanding also comes the recognition that if breast cancer represents several biologically distinct entities, then breast cancer risk assessment and treatment must take this heterogeneity into account, which complicates trial design and interpretation.
Participants felt that dealing with the discontinuation was more complicated for trial participants who had not disclosed gel use to their partners.
Further, pre-treatment biopsy may result in tumor seeding which would complicate neoadjuvant trials.
One of the key factors that complicates clinical trials of SAH is the variability of the initial injury and subsequent inflammatory response.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com