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Most importantly, these data imply that the loss of salivary flow in SS is the end result of a complicated pathological process that is poorly understood.
Age, mutated genes, radiation, smoking, chemical insults, physical injury and other systemic diseases can lead to cataract formation by initiating complicated pathological processes that result in abnormal protein aggregates and cellular disruptions in the lens [1], [2].
These results suggest that such microcirculatory disturbances are part of a complicated pathological process involving multiple, coordinated events.
The consequent encephalopathy is a complicated pathological process; however, the main cause of the deleterious cascades may be cell damage in mitochondria at the cellular level [ 3].
Therefore, cell death is a complicated pathological process, the detailed effect of physicochemical properties of crystals in cell death mode still calls for further research.
The release of the human genome sequences and accumulating databases as well as technological development for detecting large-scale gene expression profile have enabled integrated genome-wide study on complicated pathological states, such as cancers.
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His course remained severe, complicated by pathological vertebral fracture.
Further study is needed because the pathogenesis of MPE is complicated and the pathological mechanisms of association between SPP1 and MPE remain unclear.
Management of the patient was complicated by a pathological fracture of the distal third of left femur sustained during an incision and drainage when a manipulation under anaesthesia was performed at the same time for the stiff knee.
Because excessive ROS production is cytotoxic and can induce a number of pathological processes, complicated regulatory mechanisms have evolved that tightly control the activity of the phagocytic oxidase.
We chose to exclude fetal deaths in utero, because it likely represents a group of complicated births having different pathological mechanisms unrelated to placental abruption.
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CEO of Professional Science Editing for Scientists @ prosciediting.com