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While Normal mixture models are available, because of the limitation of the shape of Normal distribution (it must be symmetric and unimodal), it can require a relatively complicated model for relatively simple data.
However, our isolated and cellular mitochondrial studies in Q7 and Q111 cells point to a more complicated model for ZDON-induced protection from 3-NP, which extends beyond PGC-1α cytochrome c and mitochondrial-based metabolic compensation.
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"Whoever came up with this has no idea what my business is like". This is the common lament of managers confronted with overly complicated models for measuring productivity.
The obvious increase of knowledge using these techniques is mirrored by the huge amount of data requiring complicated models for biomathematical analysis.
It is shown that combination with two approaches to realize complicated models of building HVAC system for the application of model-based fault detection and diagnosis is a good solution.
Such complicated models allow for more detailed evaluation of management regimes, such as those based on size limits, but do not necessarily provide better estimates of MSY.
Economists use complicated models to try to trace these effects.
For complicated models and large datasets, iterative methods may be needed.
For more complicated models involving multiple unknowns, the same method could take days to weeks to compute an answer.
From a statistical point of view, data obtained from PET scans are typically clustered data, and complicated modelling techniques may be required for correct data analysis [ 25, 26].
This method represents a convenient and rapid alternative for achieving intrinsic fluorescence-based redox measurements as compared to those complicated model-based methods.
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