Sentence examples for complicated linkage from inspiring English sources

The history of selection in regions such as this one with major developmental genes often leaves complicated linkage disequilibrium patterns which add confusion to the interpretation of results.

Bayesian networks have been used in a number of settings to provide insight into the complicated linkage between variables that interact.

Although the MHC is generally believed to harbor additional T1D-associated genes, the overshadowing effect of the HLA class II genes and the strong and complicated linkage disequilibrium (LD) within that region (Alper et al. 2006; de Bakker et al. 2006) make such associations hard to uncover by conventional methodologies.

Although markers displaying segregation distortion may complicate linkage analysis [ 66], distorted loci can often be mapped, and the mapping of distorted markers may help to identify genes that have important biological functions [ 67, 68].

For more complicated data linkage, building a variable dictionary, including the SV, is very helpful when checking and analysing data.

(2) The detection of sequence-specific effects in such conditions is further complicated by linkage disequilibrium (i.e. non-random association of sequences into haplotypes).

Poor quality of some clinic data (e.g., missing or duplicate identifiers) complicated the linkage of records from different registers and tracking of women who had switched facilities [ 7], potentially under-estimating the proportions tested and enrolled in care, although mis-matches are likely to have resulted in random misclassification of outcomes.

This test problem is used to assess whether EMaO algorithms are capable of dealing with degenerate PFs and complicated variable linkages.

However, effective use of QTL alleles from wild species can be complicated by linkages among desirable and undesirable trait loci and/or by interactions of QTL with the environment (Bernardo 2008).

The complexity and diversity of glycosylation significantly complicates the linkage between genetic sequence and mature, active proteins.

Superficially this might be expected to complicate the linkage of data to clinical outcome yet further, given that even more aberrations will be identified.