The oscillator representation is a mathematically tractable model that allows one to construct complicated hypotheses that may then be addressed by physiological experiments and by detailed models.
However, the expression profiles of several important cell cycle regulators, including cyclins, appear to complicate this hypothesis.
However, we also show that this pathway association is statistically significant in only 2 out of 3 studies, complicating the hypothesis of pathway reproducibility.
But responses from natural science faculty members proved more complicated than the hypothesis had predicted.
The user can easily test complicated and interesting hypotheses on many features.
However, this hypothesis is complicated by several lines of evidence that have demonstrated telomere shortening in response to extreme amounts of exercise.
However, this hypothesis is complicated by a detailed comparison of our dataset to the second recent PD association study by Fung et al. [ Lancet Neurol 2006 5 911 916].
The testing of this hypothesis was complicated by the fact that the PI3K inhibitor used (LY294002) had significant effects on IL6 expression induced by TNFα alone, as earlier reported [ 32] and similar to earlier published results where IL17 was used to induce IL6 [ 33].
In any case, as one attempts to make the Public Goods Hypothesis more precise, the hypothesis becomes more complicated.
Fostering self-worth and hope are important goals of positive youth development (PYD) efforts, yet intervention design is complicated by contrasting theoretical hypotheses regarding the directional association between these constructs.
