Furthermore, functional DNAs are negatively charged molecules having low binding affinity with the cell membrane, which complicates entry into living cells and thus limits applications in biochemical assays and medical diagnostics.
Another limitation is the impact of specific pathogens on the adequacy of initial AB and survival could not be performed because stratification into smaller groups would complicate entry in the logistic regression model, as each group would have a very small number of cases.
Membrane proteins are synthesised directly into the lumen of the ER [20], which complicates their entry into the MHC class I pathway.
The situation at Gallipoli was complicated by the entry of Bulgaria into the war on the side of the Central Powers.
Cumbersome electronic patient record (EPR) interfaces may complicate data-entry in clinical practice.
That mission, however, might be complicated by the recent entry of some of his colleagues in the technology community, including Bill Gates, Michael Dell, Sergey Brin, and Larry Page.
The race was complicated, though, by the entry of John Y . Brown a Democrat who was a U.S. Representative and former Speaker of the Kentucky House of Representatives.
In Alaska, where Republicans are targeting Democratic Senator Mark Begich, Tea Party favorite Joe Miller is facing Lieutenant Governor Mead Treadwell in a race that could be complicated by the potential entry of another Republican: former Alaska Governor and 2008 vice presidential nominee Sarah Palin.
Tally sheets and health-centre registers, for example, involved complicated and sometimes repetitive entries that were frequently difficult to interpret.
The issue is further complicated by Russia's direct entry into the Syrian theatre last week.
