Ostensibly, the advance notice allows journalists the time to digest and understand complicated discoveries before blurting them to the poor public.
Delay of ambulation after surgery may complicate discovery of the head tremor in this case.
In forward genetic screens, heavily mutagenized genomes have additional changes, further complicating discovery of causative mutations.
Despite the potency of salivary gland extracts, the amount of crude starting material extracted from ticks is extraordinarily small, which complicates discovery-stage work.
In Uganda, civil war and poverty have complicated the discovery and isolation of the infected.
While considering baseline kinomic responses may prove complicated, the discovery of complex biomarkers, in particular those associated with kinase activities, has tremendous potential to inform research involving animal models as well as personalized medicine.
The recent timing of this tetraploidy complicates discovery and mapping of genetic markers for Miscanthus species, since alleles and fixed differences between paralogs are comparable.
Simultaneously, non-SNP genomic variants (e.g. polymorphisms at adjacent residues and micro-indels) have more complicated color-space signatures, complicating variation discovery.
As others have pointed out, a plethora of factors can before, during and after sample analysis complicate biomarker discovery and validation and lead to false discoveries [ 14].
