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First, de novo protein design has complicated the assertion that biological function is equivalent to biological structure — demonstrating the capacity to abstract active sites from natural contexts and paste them into non-native topologies without loss of function.
It's complicated, but the widespread assertion that Kennedy won a national plurality of around 112,000 is based on counting all 320,000 votes cast for eleven Democratic electors in Alabama as Kennedy votes, even though six of those eleven were rabidly anti-Kennedy and J.F.K. wasn't even on the ballot.
For assertion-reason questions, it is more complicated.
And complicated".
Trippy, complicated.
Complicated enough?
Sound complicated?
Why? "Complicated.
Complicated business.
Complicated, yes.
"It was complicated, very complicated.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com