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Exceptionally high levels of heterozygosity (0.85 % of single nucleotide polymorphisms plus sequence insertions or deletions) complicated assembly; nevertheless, 96.4%% of reads mapped back to the assembled scaffolds, indicating that the assembly included most of the sequenced genome.
This increased the number of sensor parts and further complicated assembly.
This framework represents a novel, cheap and easy solution for planning complicated assembly tasks.
The large size and mass of components with tight installation tolerances results in complicated assembly procedure.
Just think of the complicated assembly required for arranging dozens of individual keys into the laptop's frame.
Nature controls material properties by complicated assembly and structural organization of matter which contains amount of porosity.
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These samples also contain a population of genetically heterogeneous genomes with polymorphisms that complicate assembly.
This results in significant redundancy of the most abundant transcripts, compounding sequencing errors, complicating assembly, and increasing computing time.
However where multiple copies of the same IS are present within a single genome (including on the chromosome and/or plasmids), this complicates assembly of short-read data and makes IS insertion sites difficult to identify reliably.
Recursive polyploidizations may complicate assembly of Brassica genome sequences, especially if they are accompanied by frequent illegitimate recombination events that render 'islands' of paralogous DNA sequence (such as genes) homogeneous.
In B. malayi, a large amount of sequence integrated into the nematode nuclear genome from its obligate mutualist Wolbachia endosymbiont relatively recently such that it has not diverged significantly [ 5, 6], which further complicates assembly, resulting in numerous collapsed repeats and corresponding gaps in the assembly [ 5].
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