In fact, as mentioned above, the type of our model has a "micro-resolution" – events occurred in the system are described at the level of monomers (deoxy/nucleotides for DNA/RNA and single amphiphilic molecules for membrane), and the computation is very intensive for so complicated a model system like the present one.
We analyzed the data in separate age classes in order to compare the same individuals in successive age classes, eliminating individuals that did not survive to the next age class; another reason for this was to visualize differences between age classes, which could be obscured by too general or too complicated a model.
The structure condition property relationship is very complicated; a well-established model may be an effective solution.
But if publishers feel unable to "make" a book and increasingly depend on word of mouth and the new bottom-up zeitgeist it will surely complicate a publishing business model that makes massive bets on progressively fewer books in the hopes that those books reach the "phenomenon" status that pads margins and launches careers.
Direct protein-protein interactions between the involved fly TFs have also not been observed, complicating any model involving a transcription factory.
In backward selection, we begin with a complicated, flexible model and fit progressively simpler models.
Incorporating as many of these complicated interactions into a model is essential for identifying potential drug targets, as cells are remarkably robust and have built-in fault tolerance systems that may not be evident from examination of static network or interaction diagrams [ 56, 62, 63].
The fundamental idea of our novel approach is the geometry-aware object segmentation, by which an arbitrarily complicated surface model can be decomposed into a group of disjoint components that comprise branches, handles, and base patches.
All the algorithm is really doing is creating a – very complicated – mathematical model of Rembrandt paintings, and then spitting out a visualization of it according to some very carefully defined criteria.
For example, Heath points out that the Quality and Outcomes Framework applied to UK General Practice is designed on the basis of average or 'standardized' patients, and constructed on the basis of populations without co-morbidities or other complicating factors, a model which she suggests is, at best, inappropriate.
The virtual Experimental Advanced Superconducting Tokamak device (VEAST) is a very complicated 3D model, to interact with which, the traditional interaction devices are limited and inefficient.
