Even with feature length prescriptions, enumerative approaches still employ multitudes of noise features, which can degrade performance [ 23] and complicate determination of feature importance and interpretation.
Figure 1 C shows T-waves with negative undershoot components, not clearly separable from the succeeding P-waves, which would complicate determination of the end of the T-wave.
However, such hyper variability, that may occur within some VNTRs, would complicate determination of genetic relationships among strains using this method, and hence, its use in phylogenetics may not be ideal [ 45, 54].
The study by Xue et al., conducted within data from a commercial health plan, was restricted to the first 2 years following the launch of duloxetine in the US and included patients with and without baseline hepatic risks and active liver disease, complicating determinations of the association between duloxetine and liver injury.
This is a common characteristic of microbial ecologies, complicating determination and reporting of antimicrobial activity (Marsh 2004; Harrison et al. 2004; Sabater et al. 2007; Salli and Ouwehand 2015).
Removal of older (parental) CR elements from the genome within several million years of their insertion further complicates determination of the evolutionary history of retrotransposons.
This model suggests that the observed flexibility in the enzyme, which apparently complicates determination of atomic resolution structures directly from cryo-EM data, is also essential to the mechanism of ATP synthesis.
To complicate dose determinations, there is an apparent lack of dose proportionality that may be related to reduced drug availability or altered distribution with increasing dose (55).
However, inherent differences in antibody affinity and specificity issues can complicate these determinations, and protein overexpression does not reflect native conditions.
Examining long-term effect of Pi infusion on DMI could determine if competing mechanisms complicate the determination of P requirement for dairy cows.
