Sequencing data obtained from samples A and P were pooled and subjected to a publicly available sequence cleaning and validation software, SeqClean [ 71], to account for size-selection, overall low complexity analysis, and to remove poly (A T) regions, and adapters.
Sequences can be filtered by their length, quality scores, GC content, number or percentage of ambiguous base N, non-IUPAC characters for nucleic acids, number of sequences, sequence duplicates, sequence complexity (for example, to remove simple repeat sequences such as ATATATATAT), and custom filters defined by the user given a predefined grammar.
We see a lot of opportunity to remove complexity, streamline and reduce costs in a number of areas across HP".
Minority stakes were "dead money" and sold, whereas alliances with other firms were unwound to remove complexity.
"The intent behind all these changes is to remove complexity, make it easier to buy, easier to sell, easier to get things done," Ms. Whitman, the company's chief executive, said in an interview.
"It cannot act as the independent regulator you have created, enmeshed in a network of interlocking rules which require an analysis that would do credit to any rabbinical study of the Talmud … I am looking to remove complexity and obscurity in the rules, to make them effective, not to turn them upside-down".
Exploiting massive cost arbitrage: Uber is one of the many marketplaces that has emerged to remove complexity and lower cost from an incumbent industry.
Columbia Power ran through more than 350 iterations of the latest version of the SeaRay to find the optimal shape for the device and to remove complexity to minimize maintenance costs and the frequency of breakdowns miles from shore.
They are trying to react to these same forces that everyone else in the industry sees, which is how to remove complexity, how to enable agility, but they're doing it very much within their own world.
The first contained all orphans as defined by BLAST (using a threshold of 10−3), the second applied an arbitrary length cutoff of ≥150 amino acids and excluded all CDS with low complexity (highly repetitive) regions to remove likely CDS enriched in artefacts.
Low-complexity filters were applied to remove highly repetitive sequences.
