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A limitation to using APC modelling is that the models do not account for linear generational changes in the rates and given the complexity of trends, the APC models may therefore be considered a rather blunt instrument for detecting non-linear effects only.
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The complexities of predicting trends in such a dynamic system necessitate that clinicians and policy makers take time to consider who pays, and who benefits from interventions.
Depending on the number of measurements and the complexity of the time trends, more complex change patterns can also be explained by the mixed-effects models.
From Raising Our Children's Children: Room In The Heart, When I began this book, my goal was to offer grandparents and grandchildren a look at what others have been through and survived... and I hoped to raise awareness in others who may not realize the depth and complexity of this growing trend while providing a common sense outlook onto the issues.
The recent landmark case of separating domestic and bighorn sheep on the Payette National Forest in Idaho exemplifies the complexities of this trend.
Spatial Complexity: Complexity of the movement path.
The complexity of imagery reflects several trends.
The objective of the present work is that of providing the guidelines, methodology and the instruments for the observation and characterisation of the convective phenomena of heat dissipation of electrical components and how the complexity of thermal exchange follows trends, which are not linear.
Because of lack of available data about current and historical resistance rates, the complexity of forecasting antibiotic resistance trends over time and within populations, and a lack of examples on which to base methodological approaches, 23 the main simplifying assumption was that the probability of antibiotic resistance does not change over time.
Given the complexity of contemporary conservation challenges, and trends towards new ways of doing conservation that are more integrative, interactive and inclusive, the necessary 'capacity' now extends beyond knowledge of conservation science into a range of other skills and competencies.
Given the increasing complexity of mobile generation, the natural trend in system operation and management is to automate these processes, for which KPIs are the main inputs for decision-making.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com