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The increased complexity of such a model may necessitate the use of the rule-based modeling approach, which is designed for reaction networks with large numbers of proteins with complicated interactions, activities and post-translational modifications.
On closer inspection the complexity of such a model rapidly overshadows the initial appeal of the apparent simplicity of the integration message.
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BDS fails to address the complexities of such a move.
Due to the complexity of such a system, creation of physical model for system prognostics is very difficult and costly.
However, this increases the complexity of such a system.
The complexity of such an optimization depends on the model complexity.
Simplifying assumptions are often needed to cope with the complexity of such models in an efficient way, and the choice of such assumptions often leads to models that fall within a certain structural template or formalism.
The increasing number and complexity of such "bio-models" necessitate computer support for the overall modelling task.
The complexity of such animal models limits our ability to modulate the parameters that control the process of immune cell development, differentiation, and immunomodulation.
The complexity of such integrated models calls for alternative methods of solution, such as Approximate Dynamic Programming (ADP), which provide a further increase in the performance necessary for the daily operation.
Due to the almost total absence of mathematical models that fit the system and also due to the complexity of such models, the choice fell upon a statistical technique, the central composite design (CCD), to obtain the desired responses as empirical functions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com