A systems perspective, which posits that complex problems lack simple or obvious solutions, shows that prevention efforts must be based in a deeper understanding of the dynamic complexity of modifiable lifestyle risk-factors [ 19, 35].
The potential confounding factors and limitations of the study the small size and short duration of the study, the complexity of the lifestyle changes, the absence of any data on the effect on telomere length, and the lack of an independent control group make it impossible to identify causal factors.
Although generally confirming the above findings, the results were more heterogeneous due to different methodologies and the actual complexity of human lifestyle as compared with experimental animal models, where all potential confounding factors, including the frequency and composition of meals, can be precisely controlled.
"The complexity of life and lifestyle is a constraining factor," she said.
Then there's the complexity of navigating the lifestyle and how to manage your energy on the road while metabolizing the brutality of listening back to recordings of your performances and stomach the reality of knowing there's still a long way to go... It's so much about perseverance.
From this it is clear that the high resistance to commonly used antifungals by biofilm-associated C. albicans cells cannot be attributed to the actions of just one mechanism, but is rather a comprehensive mechanism reflecting the complexity of the biofilm lifestyle itself.
These behaviours are in their turn affected by numerous variables, such as the nature of the patient-physician relationship, complexity of regimen, disruption of lifestyle, emotional support, financial resources, education in self-management skills, cues to action, perceived barriers, locus of control and motivation[ 36].
The complexity of the etiology in lifestyle issues may have been neglected in the past.
Leaders in obesity prevention suggest these modest results reflect a failure to anticipate the complexity of drivers of population lifestyle behaviours, the potential plasticity of risk factors when addressed in isolation, and post-intervention effect dropoff.
Since its first release, the annotation not only presents an overview of the complexity of the pathogen's lifestyle, but also has served as a guide for experimental design.
