An arsenal of reconstructive methods are available depending on the size and complexity of the defect.
The propensity of desmoid tumors to develop in scars has led some surgeons to limit the complexity of desmoid defect reconstruction as a strategy for avoiding desmoid recurrence.
Nevertheless, the applicability of autologous bone transfer might be limited within the medically compromised patient or because of the complexity of the defect and the required size of the graft to be harvested.
Minimally invasive techniques have had limited application in congenital cardiac surgery, primarily due to the complexity of the defects, small working area, and the fact that most defects require exposure to intracardiac structures.
Given the higher mortality related to immature organ function and a greater complexity of heart defects, the application of the m/SOFA score, a less invasive and simple way to assess organ damage, is especially suitable in neonates.
The large number of mouse genetic models in which NTDs arise as part of the phenotype emphasize the possible genetic complexity of these defects and provide insight into the multiple molecular requirements for neural tube closure (3, 6, 7).
Recent studies in humans and model organisms have shed new light on the complexity of meiotic defects, providing evidence that the age-related increase in errors in human females is not attributable to a single factor but to an interplay between the unique features of oogenesis and a host of other endogenous and exogenous factors [ 3].
The complexity of hydrogen-related defects together with the existence of many native defects in oxides, makes it difficult to directly observe their fingerprint.
Graphene oxide (GO) presents a unique chemical complexity due to the number of defect sites and chemical groups introduced by the harsh oxidative treatment.
To tackle the effects of chemical complexity in defect dynamics and radiation response, we present a computational study on swift heavy ion induced effects in Ni and equiatomic Ni -based alloys (Ni50Fe50, Ni50Co50) using two-temperature molecular dynamics simulations (2T-MD).
