Sentence examples for complex turnover from inspiring English sources

Following the fate of less than 16 neurons in the complex turnover of the central nervous system is a daunting (and whoever dissected a Drosophila pupa knows, messy) task.

Plots of surface-bound and internalized radiotracers indicate similar behavior up to 24 h p.i. for both 124I-J591 and 89Zr-J591, withetheffectct of differential clearance rates becoming apparent after about 35 h p.i. Estimates of J591/PSMA complex turnover were 3.9 90.5 × 1012 (for doses from 60 to 240 μg) molecules per hour per gram of tumor (20%% of receptors internalized per hour).

We recently demonstrated that LRP-1 contributes to carcinoma cell invasion by subtly controlling adhesive complex turnover [17].

We further demonstrated that the LRP-1-dependent regulation of MAPK signaling organizes the cytoskeletal architecture and mediates adhesive complex turnover in cancer cells.

A molecular regulation of the slit diaphragm complex turnover via nephrin phosphorylation and endocytosis was first described by Quack and coworkers [13].

Apart from influencing the mechanical stability of the cytoskeletal connection, vinculin interacts with numerous (protein) ligands and appears to fulfil a number of different functions in cell contacts, affecting regulation of adhesion complex turnover as well as signal transduction [6], [7].

Complex I turnover becomes restricted by the lack of electron acceptor ubiquinone.

However, we cannot rule out that the loss of binding to the WASH complex alters turnover of the WASH complex on the endosome or affects the endosomal subdomain organization of the retromer and WASH complexes.

Because the residual time of secreted proteins within the secretory pathway is limited, the formation of Fam20A/Fam20C complex, whose turnover number (kcat) is dramatically increased, may reflect an important mechanism to achieve high stoichiometry of secreted proteins phosphorylation.

Alternatively, complex I turnover (NADH ubiquinone oxidoreduction) is a well-defined reaction that occurs at up to ∼200 s–1 (∼400 electrons transferred down the chain per second) in isolated complex I. Consequently, the maximum possible half-transfer time is 1.7 ms (if, which is highly unlikely, intramolecular electron transfer is fully rate limiting).

Second, through hydrolysis via a complex lipid-turnover pathway, several specific hydrolases are involved in the turnover process, including sphingomyelinases (SMases) and glucocerebrosidase (GCase).