Sentence examples for complex to induce from inspiring English sources
The ability of the complex to induce DNA cleavage was studied by gel electrophoresis techniques.
In 2012, Jinek et al. first demonstrated that the Cas9 protein from Streptococcus pyogenes (SpCas9) can bind with a tracrRNA-crRNA RNA complex to induce DSBs in vitro at a target DNA sequence by Watson-Crick base pairing of crRNA and target DNA (Jinek et al., 2012).
This ATM/NEMO/RIP1 complex cooperates to activate cytoplasmic adaptor protein TRAF6 (Hinz et al., 2010) and Ser/Thr kinase, TGF-β-activated kinase 1 (Tand) and IKK complex to induce NF-κB activation through multiple signal transduction mechanisms depending on the severity of genotoxic stress and cell type (Wu et al., 2010).
β-catenin is a multifunctional protein that, upon activation, can act as a cofactor for the TCF/LEF transcription factor complex to induce or enhance cell proliferation [4].
In the nucleus, β-catenin binds to and activates the TCF/LEF transcription factor complex to induce the expression of wnt-pathway genes, such as, EphB2, EphB3, TCF4 and LEF1.
The evidence also indicates that the molecular characteristics of the microbe and the host play a fundamental role in the conformation of the appropriate TCR/pMHCII complex to induce sterilizing immunity.
Additionally, to reveal possible drug-drug interactions that might dramatically influence the applicability of the studied complexes as drugs, the capability of the presented complexes to induce major drug-metabolizing cytochromes P450 was studied.
In the current study we analyzed the potency of two titanium salan complexes to induce cell death in C3 cells in vitro and tumor regression in C57BL/6 mice.
It recruits polycomb repressive complexes to induce epigenetic transcriptional repression [ 82].
HOTAIR interacts with chromatin-remodeling complexes to induce heterochromatin formation in different genomic loci thus silencing gene expression [ 12, 13].
We suggest that E1A regulates the ability of CBP/p300 APC/C complexes to induce S-phase entry, and promote mitosis.
