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Nick Boles sounded the first notes of funeral dirge when he admitted that the scheme, which involves local people designing and signing off new housing schemes, was too complex to function.
The arrangement also permits the complex to function in the disposal of misfolded proteins that normally reside in the cytosol.
Because multisite phosphorylation has been shown in some cases to confer ultrasensitivity onto cell signaling processes [22], [23], one interesting possibility is that phosphorylation of Cdc24 by Cla4 may allow the Bem1 complex to function in a switch-like manner to induce cell polarization.
Importantly, this caging effect of Hp allows the Hb/Hp complex to function as a protective sink for reactive oxygen species within Hb- and H2O2-exposed tissues.
At the same time, by generating spacer promoter transcripts, CTCF is 'feeding' NoRC with its 3' end degradation product, allowing this protein complex to function in a second epigenetic rRNA gene silencing mechanism.
In addition, cyclases and hydroxylases are thought to form a protein complex to function; thus, the down-regulation of TaLCYB may impair protein complex formation and influence the biosynthesis of lutein or other carotenoids [ 41].
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Both core and attachment proteins are equally necessary for complexes to function.
First, transcription factors can form various complexes to function in a tissue-specific manner in different contexts.
On the basis of our results, we propose these complexes to function as a metabolon, which optimises protein digestive and absorption processes at the brush-border.
Since microRNAs must be associated with a RISC complex to have function, we identified candidate microRNAs by identifying them in immunoprecipitated Ago2-containing complexes.
We also find that, in general, the core and attachment components of protein complexes are equally important for the complex machinery to function.
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