Sentence examples for complex to disrupt from inspiring English sources

For instance, activated ErbB2 is capable of binding to Par6 and thereby promotes the disassociation of the Par3 aPKC Par6 CDC42 complex to disrupt epithelial polarity (Aranda et al, 2006).

The use of miniSOG for CALI was demonstrated [57], in which miniSOG was fused with the succinate dehydrogenase complex subunit of the mitochondrial respiratory complex II to disrupt complex II activity.

Microsoft described the action as its "most complex effort to disrupt botnets to date".

The activated ErbB2 receptor tyrosine kinase was shown to signal through the polarity complex Par6 aPKC to disrupt apical basal polarity in breast epithelial cells (Aranda et al, 2006).

Here, we overerexpressed the p50-CFP subunit of the dynactin complex, known to disrupt ER-to-Golgi transport (Valetti et al. 1999).

Supramolecular chemistry principles have been used to develop new materials, molecular sensors, and multimolecular complexes designed to disrupt protein-protein interactions.

These complexes help to disrupt the ordered chromatin structure, causing local release of nucleosomes and increases in the levels of activation histone marks.

However, complex interruptions seem to disrupt these processes and cause search to resume in locations that have already been examined.

Thus inhibiting the expression of a subunit of a protein complex is very likely to disrupt the function of that complex.

Inactivation of atypical protein kinase C, a component of the Par complex, cooperates with ErbB2 to disrupt polarized epithelial cells, suggesting that the Par complex is a mediator of ErbB2-induced effects on polarized epithelial cells.

Metformin has been shown to disrupt complex I of the electron transport chain that is used by cells to generate energy.