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CRF acts directly on neurons in key regions of the central nervous system (e.g. bed nucleus of the stria terminalis and amygdalar complex) to coordinate the behavioral stress response through the activation of two receptor subtypes [15].
BRCA1 functions early in HR, interacting with nucleases, including CtIP and the Mre11/Rad50/NBS1 (MRN) complex to coordinate DNA end resection to form single-stranded DNA [ 1].
The surface nucleolin in the 500-kDa complex should be associated, directly or indirectly, to an integral membrane protein partner that holds this complex to coordinate clustering of surface nucleolin along with active endocytosis of various nucleolin-binding ligands via lipid rafts [ 10, 17, 19].
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Our findings suggest a general function for chromatin-associated lncRNAs in recruiting ASH1L or other chromatin-remodeling complexes to coordinate chromosome structure and gene expression.
The existence of these protein complexes also raises the interesting possibilities that, in proliferating cells, condensins interact with chromatin-remodeling complexes to coordinate cell-cycle progression and/or transcriptional regulation to changes in global chromosome compaction states.
We propose that these multi-layered interactions at the leading edge guide the assembly of the actin nucleation and elongation machinery into supramolecular complexes to coordinate their activities for the efficient construction of force-generating actin networks.
FLNs could serve both an enzymatic function not yet identified and/or additionally act as a metabolic sensor in PEP complexes to coordinate gene expression with metabolic status of the plastid.
Calculations show that the Ru2III,III complex prefers to coordinate six picoline ligands ([(L Ru2III,III(pic 6]), and therefore the energy of this complex was set to be zero.
This is the first study to extract and use that complex information to coordinate arm movements in real time, Contreras-Vidal says.
An aide apparently working for Chris Perkins, a Republican candidate who unsuccessfully challenged Democratic incumbent Rep. Gerry Connolly (D-Va)., pleaded guilty to orchestrating a complex scheme to coordinate super PAC fundraising while serving as a campaign manager.
The cellular and molecular processes that coordinate blastema formation are poorly understood, likely because it is a complex process, requiring tissues of an anatomically complex amputation stump to coordinate wound healing, progenitor cell recruitment, cell proliferation, and tissue patterning.
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