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Because more than one cell type is present in xylem, it is called a complex tissue.
Such scaffolds are required to reproduce more complex tissue structures.
The creation in vitro of vascularized skeletal muscle represents a first step to the engineering of more complex tissue architectures.
Furthermore, the lab is also greatly interested in creating complex tissue microstructures through use of functional biomaterials and projection microstereolithography.
The retina is a complex tissue in the back of the eye that contains the rod and cone photoreceptor cells.
Most representatives lack complex tissue organization, yet they show considerable diversity in form and ecology.
Purified matrix proteins provide a 3D scaffold that better mimics the in vivo situation; however, these are far removed from the complex tissue composition seen in vivo.
This serial SGA approach enables spatial transcriptional profiling in complex tissue samples at single cell resolution, and can be easily implemented for as many as a hundred genes.
We have a limited understanding of how these interactions look in three dimensions, vary across cell types in complex tissue, and relate to transcription.
Bone is a highly complex tissue that has structural, mechanical, and metabolic functions.
Creating biological interfaces between mechanically dissimilar tissues is a key challenge in complex tissue engineering.
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