Sentence examples for complex of genomic from inspiring English sources

In eukaryotes the complex of genomic DNA and nucleosomes, referred to as chromatin, in most cases represses gene transcription (Razin 1998), because it occludes binding sites of DNA-binding proteins.

Petersen, D. C. et al. Complex patterns of genomic admixture within southern Africa.

MiRNAs demonstrate complex patterns of genomic organisation with both intergenic and intragenic miRNA genes [22], [23].

A complex collection of genomic alterations occur during tumor cell evolution, including mutations, translocations, and copy number alterations.

The complex organization of genomic DNA is an important feature of eukaryotic cells.

Since each MC sample typically involves a complex reshuffling of genomic elements, the computational cost is extremely high.

These repertoires are the product of a complex sequence of genomic events followed by cell- and organ-level selection (Box 1, Figure  1).

GeneBase was developed within the FileMaker Pro Advanced environment (FileMaker, Santa Clara, CA, USA), which has already been proved useful for complex parsing of genomic data.

However, in our experimental conditions, CDDP did not induce apoptosis nor necrosis, likely because SKOV3 cells carry a complex set of genomic alterations, which include HER2/neu amplification, mutation of PI3KCA and p53 null.

Data from HER2-amplified tumors were compared to data from other subgroups of BC, shedding light on a complex landscape of genomic alterations in a clinically important disease entity.

It is clear that the genomes of BRCA2 mutated breast cancers classified as diploid are extensively altered, and individual examples are presented here to demonstrate complex patterns of genomic changes.