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These findings shed new light on the etiology of foot deformity in diabetes and suggest a more complex nature of development, potentially involving anatomical and physiological predisposing factors.
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It raises a challenge to policymaking, which will need to engage with the interdependent and complex nature of adolescent development embedded in context and evolving over the life course.
Our study was primarily limited by sample size of the assessment cohort, the duration of the curriculum, the short-term follow-up, and the complex nature of NTS development.
Due to the complex nature of the development of pharmaceutical formulations, some computer based optimization techniques have been proposed in the literature.
Due to the complex nature of limb development, it has been proposed that limbs can be lost but not regained [ 29- 31].
Owing to the complex nature of cancer development and progression, it is becoming increasingly clear that no single therapeutic modality is likely to be curative.
Given the complex nature of hypoxia development and its impact on tumour progression and treatment response, it remains highly important to make additional comparative studies and to relate [F]FMISO measurements with outcome.
Due to the complex nature of the development of T2D, the diversity of exercise training regimens, and wide range of physiological adaptations to exercise, it is not unexpected that reports regarding the mechanisms that may lead to the cardiac response to exercise training are diverging.
Due to the complex nature of cartilage development, it is critical to understand each step involved in regulation of this process, as there are many acquired and inherited cartilage diseases resulting from disturbances in this pathway, including glucocorticoid-induced growth retardation and human chondrodysplasias [ 6- 8].
It has recently been suggested by Pietzsch et al. [ 20] that the complex nature of medical device development necessitates a formal stage-gate approach to development as this industry is characterised by high technology development, strict regulatory requirements and complex reimbursement processes.
Starting with ancient Israel's radically new conceptions of the divine, morality, and history, this course explores the complex nature of Judaism and its development as a religion and culture over millennia--a development marked by internal debates and external challenges to continuity and survival.
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CEO of Professional Science Editing for Scientists @ prosciediting.com