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Periodontal diseases are complex, multifactorial disorders.
In recent years, genetic studies have provided substantial evidence supporting the notion that primary headaches are complex, multifactorial disorders.
IBDs are complex, multifactorial disorders in which the body loses its tolerance to its gut microorganisms.
NTDs are known to be complex multifactorial disorders arising from an array of genetic and environmental interactions.
Similar conclusions have been reached about a host of physical disorders, such as heart disease, diabetes, and allergies, with geneticists talking of complex multifactorial disorders (Sing & Reilly 1993).
The identification of the genetic susceptibility variants underlying complex multifactorial disorders requires extensive efforts including large patient cohorts and cumbersome analytical tools.
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Insulin-dependent diabetes is a complex multifactorial disorder characterized by loss or dysfunction of β-cells resulting in failure of metabolic control.
Therefore the current theory explains headache like a complex multifactorial disorder with both predisposing genetic factors and environmental factors contributing to the attacks [70].
The occurrence and development of EH are regarded as a complex multifactorial disorder resulted from genetic and environmental factors, as well as their interactions [1].
Depression is currently considered as a complex multifactorial disorder, where the risk factors from multiple domains are related and interacting with each other.
Glioblastoma is a complex multifactorial disorder that has swift and devastating consequences.
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