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Functional relationships between proteins can be identified as direct interactions, complex memberships or relatively close connections in the network of protein-protein interactions or interactome network.
Consistent with previous results on protein complex memberships [ 21, 22], we identified a physical interaction between PALB2 and MRG15.
Functional relationships between proteins can be defined as direct interactions, complex memberships or relatively close connections in the interactome network.
Protein complex memberships are represented as a matrix Z, where each entry z ij indicates that the i th protein is in the complex j.
By considering the pairwise similarity between proteins obtained by a graph diffusion kernel [ 72], the posterior distribution of Z is further inferred to indicate the protein complex memberships by the Gibbs sampling.
Constraints for BioPAX semantics : These constraints implement non-trivial reasoning, such as identifying inputs and outputs of a Conversion, linking entities through recursive homology relationships also taking complex memberships into account or detecting syntactically invalid structures like an input to a Conversion also being a controller.
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An air of exclusivity extends to a number of private shooting and sports clubs that have complex membership requirements and waiting lists of up to five years.
The genetic algorithm which is an efficient and systematic method was employed in the design of fuzzy model for optimization of the poorly understood, irregular and complex membership function with improved performance.
The only disadvantage of this method is that it is computationally difficult for complex membership functions.
The notion of the complex membership function proposed by Tamir et al. in [19] seems to be suitable.
The complex membership function is defined as nu(t)=nu_{1}(t)+mathrm{i}nu_{2}(t), where (nu_{1},nu_{2}:mandbb{R}rightinmathbb1]) and (tinmathbb {R}).
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