Sentence examples for complex heritability from inspiring English sources

Therefore, despite evidence for their collective functional and clinical relevance, our results emphasize the low predictive value of rare GCKR variants in individuals and the complex heritability of lipid traits.

These diseases have complex genetic heritability with many genes giving modest contributions to the disease initiation and perpetuation.

It is entirely plausible that a proportion of IBD and other complex disease heritability unaccounted for by common variation lies within higher risk rare variants.

Common-frequency variants explain only a small proportion of complex-trait heritability.

Furthermore, a meta-analysis of all findings from behavioural genetics, i.e. not just for educationally-relevant traits, also suggests a complex picture with heritability, shared environment and non-shared environmental factors all playing an important role in explaining human behaviour (Haworth et al. 2011; Branigan et al. 2013; Polderman et al. 2015).

Skeletal growth during fetal life and infancy is a complex trait with heritability estimates of 26 72% (4).

Smoking as a substance use disorder is a complex disease with heritability influenced by numerous common polymorphisms, each with only a small to moderate influence on the overall liability to the disorder [ 45].

It was titled Finding the Missing Heritability of Complex Diseases.

Schizophrenia is a complex disorder with high heritability.

Idiopathic generalized epilepsy (IGE) is a complex disease with high heritability, but little is known about its genetic architecture.

Variance-component methods that estimate the aggregate contribution of large sets of variants to the heritability of complex traits have yielded important insights into the genetic architecture of common diseases.