Sentence examples for complex genetic abnormalities from inspiring English sources
The broad variability in shape, size, and location is most likely due to underlying complex genetic abnormalities.
Both inherited disorders and irradiation are rare occurrences, accounting for less than 10% of all gliomas and suggesting that complex genetic abnormalities combined with unknown environmental factors predispose individuals to glioma development.
In contrast to the findings that disruptive mtDNA mutations, in particular in genes encoding complex I subunits, are fairly common in oncocytic tumors, we did not identify a large number of nuclear-encoded complex I genetic abnormalities, suggesting that mutations in these genes do not play a major role in oncocytic thyroid cancer.
MM is characterized by complex genetic and epigenetic abnormalities [ 13, 14].
Cumulative evidence supports the hypothesis that PD is the result of complex interactions among genetic abnormalities, environmental toxins and mitochondrial dysfunction [ 4– 6].
The breakthrough is expected to reduce the complexity of identifying genetic abnormalities, which in turn could advance understanding of many diseases, researchers said.
Our results demonstrate that these specific genetic abnormalities are complex, heterogeneous, and translate into a gene expression profile that defines the biological behaviour of each type of NBT.
In mammals, aneuploidy has been linked to cancer progression, which, like cancer development, is a complex process involving functional and genetic abnormalities.
With the progression from monoclonal gammopathy of undetermined clinical significance to myeloma, several complex genetic events are involved including cytogenetic abnormalities, primary or secondary chromosomal translocation, and activation of oncogenes.
These findings suggest that underlying genetic abnormalities may be more complex than previously assumed.
In general, deafness differs from many other "complex" genetic diseases in that the hearing loss usually results from abnormalities in single genes or gene pairs.
