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More complex fragmentation patterns are observed for the fragmentation of the -OSO3-TCE group.
In contrast, the fragmentation pathways of TCE PCB sulfates diesters investigated become more complex with increasing degree of chlorination in the biphenyl rings (e.g., 5 vs. 8 as discussed above), which is mainly due to the more complex fragmentation of the biphenyl rings part of the TCE PCB sulfates diesters.
When prothrombin activation by factor Xa is analyzed by SDS-PAGE a complex fragmentation pattern is observed, since both factor Xa and the generated thrombin can each cleave prothrombin twice [5].
The rest of the spectra display a quite complex fragmentation pattern but are similar for all four compounds.
Unfortunately, metabolites do not provide the complex fragmentation patterns that peptides do, making their identification somewhat more difficult.
The proteomics analysis of glycopeptides is made even more tedious by the fact that MS/MS data rarely allow the confident identification of peptide sequences due to the relatively large molecular weights of glycosylated peptides [ 65] and the complex fragmentation that originates from both peptide and glycan cleavages [ 14].
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(189) In contrast to ubiquitin, C-terminal tryptic fragments of SUMOs are very large and give rise to complex overlapping fragmentation spectra when analyzed by mass spectrometry.
But I worry that the home secretary's assumption that volunteers can fill the gap between expectation and delivery is based on a view of neighbourhoods that does not match the complex social fragmentation often loosely and inaccurately described as a "community".
Compared to conventional plasma spraying, SPS and SPPS are by far more complex because fragmentation and vaporization of the liquid control the coating build-up mechanisms.
However, our study cannot differentiate whether PGZ-induced complex I fragmentation was the result of the reduced amount of prohibitin or, on the contrary, prohibitin bound to complex I was reduced because PGZ had decreased fully assembled complex I.
The recently popularized MALDI-TOF-TOF mass spectrometer yields a complex MS/MS fragmentation pattern difficult to characterize by manual de novo sequencing method on a proteomics scale.
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