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We first examined the distribution of complex complexity, the number of unique proteins in a complex.
Because of these constraints, numerical boundaries were discovered when we related properties such as protein length to complex complexity.
Information needs were classified as simple, simple to complex, or complex (complexity rating 1 to 3 respectively).
These results concerning dN/dS ratios and gene conservation portrays similar relationships between gene evolution, complex complexity and participation at different time and constraint scales.
In particular, as complex complexity increases, the mean dN/dS ratios of proteins in complexes tend to stabilize towards the mean of this skewed distribution.
Nevertheless, there also seems to be an asymptotic bound for mean dN/dS ratios as complex complexity increases and dN/dS ratios as complex participation increases.
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In this study, we focus on two characteristics of complexes: the complexity of a complex as represented by the number of unique proteins in a complex and the number of complexes a particular protein participates in.
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