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miRNA regulating target gene expression by altering the stability of the transcript and/or interference with the translational process adds another level of complexity that must be considered in dissecting the complex cascade of events that follow nerve injury during and after the development of chronic pain.
Cardiac regeneration requires a complex cascade of events.
In mammals, tissue regeneration is accomplished through a well-regulated, complex cascade of events.
Cerebral development involves a complex cascade of events which are difficult to visualize and quantify in vivo.
Scaffolds for tissue repair must provide structural and biochemical cues to initiate the complex cascade of events that lead to proper tissue formation.
In the meantime, evidences indicate that bone formation is a complex cascade of events, in which time-dependent expression of multiple growth factors is involved.
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In conclusion, we recognize the difficulties inherent in interpreting causes and mechanisms responsible for CRC-associated TP53 mutations, which are the end result of complex cascades of events.
Once the calcium ions enter the tail, they initiate an unknown and seemingly complex cascade of phosphorylation events that, as described above, result in the hyperactivated motility that is an essential prerequisite of successful fertilization (Visconti et al., 1995).
A complex cascade of molecular events is set in motion during cerebral ischemia and culminates in neuronal cell death some of major events are shown in Fig. 11.
Growth factors play an important role in the complex cascade of tissue events in periodontal regeneration, although optimal methods of delivery remain to be identified.
Ischemic stroke caused by cerebral artery occlusion results in the activation of a complex cascade of pathophysiologic events, including brain edema, blood-brain barrier disruption, oxidative stress and neuroinflammation [1].
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complex whirl of events
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complex cascade of hormones
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complex confluence of events
complex labyrinth of events
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