Sentence examples for complex array of interactions from inspiring English sources
The complex array of interactions that characterize social insect colonies can be considered an emergent property of the social group and earlier models suggest that selection at the colony-level shapes these networks of interactions [56], [57].
At LT, 6 different miRNAs potentially targeting TIMP-2 and TIMP-3 are significantly up or downregulated which is highly susceptible to affect the complex array of interactions between MMPs and between MMPs and their targets (extracellular matrix macromolecules, cytokines).
Furthermore, experiments in cell lines do not reflect the complex array of interactions among malignant and stromal cells, secreted factors and extracellular matrix proteins taking place in the tumor microenvironment, which also modulate the hormone actions.
Members of HER family take part in a complex array of combinatorial interactions through the formation of homo and heterodimers between the different family members and not only the preferred heterodimerization partner HER2, but also EGFR and recently HER3 have been defined as important therapeutic targets in breast cancer [6].
Of course, a complex array of intergradient interactions is expected to occur in nature, leading to multidimensional complex gradients.
The activity of RTKs and their downstream targets is regulated by a complex array of kinase interactions and feedback loops [ 10, 11].
More in general, they further stress that PTCL/NOS is a neoplasm characterized by a complex array of molecular interactions at the genome, transcriptome and proteome levels, which eventually have an important role in the process of lymphomagenesis.
Among the most important and broadly studied of these roles is reversible phosphorylation of the C-terminal domain (CTD) of RNA polymerase II, part of a complex array of CTD/protein interactions that coordinate the RNAP II transcription cycle.
The present tumor slice model represents a heterogeneous combination of epithelial and stromal cells, in which the complex array of reciprocal interactions taking place in the tumor microenvironment, including cell-cell contacts and a variety of secreted factors, might modulate the overall response to 1,25(OH)2D3.
This complex array of molecular interactions involves a number of cell types including the endothelial cells and their attendant perivascular supporting cells (pericytes and vascular smooth muscle cells [vSMCs]), and inflammatory cells, and they are profoundly influenced by the presence of growth factors, cytokines, chemokines and potent vasoactive factors.
These materials typically exhibit an extremely complex array of chemical structures and interactions across a large range of size- and timescales, resulting in molecular signatures that reflect the fundamentals of chemical binding rather than those of their precursors.
