These results suggest the potential application of the Exotest in clinical settings using whole plasma and avoiding the complex and time consuming procedure of exosomes purification.
However, disadvantages such as significant chemical additives, solvent losses, complex equipments, large secondary wastes, prefiltration problems and time consuming procedures, limit the application of most of these techniques.
Unlike other benchmark assessments, our version has four different scales, and this may require more complex and time-consuming procedures for assessors and assessees.
As resolutions of racemic mixtures are complex and time-consuming procedures, the chiral pool of natural α-amino acids is limited and catalysts or chiral auxiliaries cause high costs, all of these strategies have their limitations when applied on an industrial scale (Weiner et al. 2010).
Current detection and identification of micro-organisms is based on either rather unspecific rapid microscopy or on more accurate but complex and time-consuming procedures.
New drug development is a complex and time consuming process.
The design of a flight vehicle is a complex and time-consuming procedure requiring the integration of many engineering technologies.
Localisation and navigation of the robots are usually performed with optical or magnetic localisation spheres, requiring a pre-procedure import and processing of the 3D data to the robot's workstation, which can be a complex and time-consuming procedure.
An optimal clinical assessment of nutrition status necessitates a detailed medical history, anthropometric measurements, laboratory tests, and dietary interviews, thus being a complex and time-consuming procedure [ 1, 3, 13].
When using the lDDT score to evaluate predictions, it is not necessary to split the target structure in separate domains, whose identification can be a complex and time-consuming procedure.
Therefore, being able to exclude the tumour risk in these patients would involve either a mutation study of the PAX 6 gene, which is a complex and time-consuming procedure, or a cytogenetic analysis of the 11p13 region.
