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A combination of cooperative action and distinct activity is probably the best explanation for the complex and divergent pathways of progesterone action in normal and malignant physiology.
See related research by Rungatscher et al., http://ccforum.com/content/17/5/R245 Lowering core temperature has complex and divergent effects on the myocardium, stimulating or inhibiting contractility and heart rhythm through several different mechanisms.
Such a comparative analysis reveals highly complex and divergent expression patterns for the majority of P450s, and provides novel clues on P450 functions, related pathways, and corresponding regulatory networks.
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All the plans were quite complex and deeply divergent.
After the verdict, interviews showed complex and often divergent feelings: an appreciation of many officers and the stresses they face, but continuing anger at the abusive behavior of others.
This frame draws attention to the complex and sometimes divergent perceptions and experiences within a department (i.e., the culture of the department is not the same for all individuals all of the time).
Germline development and gametogenesis proceed in multiple processes that are complex and apparently divergent among metazoans.
However, in the policy and health systems research (HPSR) literature, conceptual confusion is reflected by the interchangeable use of terms such as 'complicated' and 'complex' and divergent definitions of what makes a problem, an intervention or a specific setting complex.
The complex and no doubt divergent answers to this question will soon manifest in commentaries and panel discussions at places like the World Health Assembly, which starts next week.
The effects of E on ER are exerted through a complex array of convergent and divergent signaling pathways that mediate genomic events involved in regulation of mitogenesis, differentiation and apoptosis [3], [4].
The DHA2, ARN and GEX gene lineages spanning the species of the Saccharomyces complex, CTG complex and the early-divergent hemiascomycetes, P. pastoris and Y. lipolytica, are detailed bellow.
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CEO of Professional Science Editing for Scientists @ prosciediting.com